Activators and Inhibitors of Protein Kinase C (PKC): Their...
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pkc beta Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways..
kubet đăng nhập top 1 PRKCB (Protein Kinase C Beta) is a Protein Coding gene. Diseases associated with PRKCB include Diabetic Macular Edema and Macular Retinal Edema. Among its related pathways are Prolactin Signaling and Autodegradation of the E3 ubiquitin ligase COP1.
alo789 top.com In vivo, PKC-beta-1 colocalized with AR and LSD1 on target gene promoters and phosphorylated H3T6 after androgen-induced gene expression. RNAi-mediated knockdown of PKC-beta-1 abrogated H3T6 phosphorylation, enhanced demethylation at H3K4, and inhibited AR-dependent transcription.